We make the most of our distinctive mix of businesses to drive continued growth. In 2014 we added our new Ophthalmics business. With the help of specialists such as Dr. Joe Tauber and Dr. Howard Mayer (Shire), we are working on a number of developments in this specialist area, notably our potential treatments for Dry Eye Disease and for the prevention of retinopathy of prematurity (ROP).
For Shire, growth is both a means and an end. Sustained high growth across all our business units enables us to fuel further R&D and in turn develop innovative new products for patients with unmet needs. Growth drives our revenues and profits. It adds to our momentum. Growth, too, is a great marker of our progress, as we strive to achieve our 10 x 20 target to double our product sales to $10 billion by 2020.
We are on track to file lifitegrast in 2015, and recently received Fast Track designation from the FDA on SHP607
With our focus on rare diseases and other speciality conditions we are always looking to build on our existing strengths and extend our expertise to new and complementary areas. Through our acquisition of Lumena, for example, we are in clinical trials with SHP625 for the treatment of Alagille Syndrome, collaborating with patient advocates like Cindy to advance our understanding and capabilities and help patients in need.
Innovation is the lifeblood of our current and future success. We seek to focus our innovation across areas with high medical need. To this end, we aim to expand our rare disease expertise and offerings through research and partnerships, and to extend our existing portfolio of products to new indications and therapeutic areas.
By maximizing efficiency across Shire we free up greater resources to focus on researching, developing and bringing to market much needed treatments for patients. One example of improved efficiency is the consolidation of our global hubs into our US Operational HQ in Lexington, MA and an International Operational HQ in Zug, Switzerland.
Our ongoing focus on efficiency enables us to reinvest in continued growth. The leaner and more agile we are as an organization, the more able we are to fuel and fulfil our purpose to enable people with life altering conditions to lead better lives.
1This is a Non GAAP financial measure. For reconciliation to US GAAP please see page 166 of the Annual Report.
2Results from continuing operations including ViroPharma Inc. and excluding DERMAGRAFT.
From our new International Operational Headquarters in Zug, to our sales forces around the world, we work together as a close-knit, resilient team dedicated to achieving high performance. Our people are highly loyal and committed. Throughout Shire, we strive to create a great place to work, where people can perform and progress to their full potential. Our shared purpose is to help people with life-altering conditions lead better lives.
Our people are at the heart of our journey to become a leading biotech delivering innovative global medicines to patients with rare diseases and other specialty conditions. We focus on attracting and retaining great people and giving them an environment where they are encouraged to excel.
as at December 31, 2014
as at December 31, 2014